NUMERICAL INVESTIGATION OF THE ENERGY FLEXIBILITY OF DIFFERENT HEATING AND COOLING SYSTEMS


cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin.

BACKGROUND: Mesenchymal stem cells (MSCs) are a pluripotent cell type that can differentiate into adipocytes, osteoblasts and other cells.The reciprocal relationship between adipogenesis and osteogenesis was previously demonstrated; however, the mechanisms remain largely unknown.METHODS AND FINDINGS: We report that activation of PKA by 3-isobutyl-1

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